Genetics of Substance Use By Michael M Vanyukov

Publisher: MEDICAL BOOKS

Availability: In Stock
SKU: 49571
Number of Pages: 231

Rs.570.00

Rs.895.00

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Understanding the genetic underpinnings of substance use is crucial in elucidating its complexities and developing effective intervention strategies. Michael M Vanyukov's comprehensive work delves into the intricate relationship between genetics and substance use disorders, offering insights into both genetic predispositions and environmental influences.

Key Points:

Genetic Vulnerability: Certain genetic variations predispose individuals to increased susceptibility to substance use disorders.
Polygenic Risk Scores: Assessing multiple genetic markers helps in predicting an individual's risk profile for different substances.
Gene-Environment Interplay: Environmental factors interact with genetic predispositions, influencing the likelihood of substance use initiation and escalation.
Neurotransmitter Systems: Genetic variations in neurotransmitter pathways (e.g., dopamine, serotonin) play a significant role in addiction susceptibility.
Epigenetic Modifications: Environmental factors can alter gene expression through epigenetic mechanisms, impacting substance use behaviors.
Heritability Estimates: Studies indicate a substantial genetic component in addiction, with heritability estimates varying across different substances.
Candidate Genes: Identification of specific genes (e.g., DRD2, OPRM1) associated with substance use disorders aids in targeted research and treatment approaches.
Pharmacogenetics: Genetic variability influences individual responses to pharmacological treatments for addiction.
Gene-Environment Interaction Studies: Research focusing on how genes interact with environmental factors (e.g., stress, peer influence) provides deeper insights into addiction etiology.
Implications for Treatment: Integrating genetic information into treatment plans facilitates personalized approaches, improving outcomes in addiction recovery.

Genetics plays a pivotal role in shaping susceptibility to substance use disorders, interacting intricately with environmental factors. Michael M Vanyukov's exploration underscores the multifaceted nature of addiction, paving the way for targeted interventions and personalized treatment strategies.

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